Vol. 4, Issue 4 (2019)
Pharmacognostical evaluation of Spiny coriander (Eryngium foetidum L.): A traditional culinary and ethnomedicinal herb
Author(s): Shashi Prabha, Sapam Athoibi, Myrene R Dsouza
Abstract: Eryngium foetidum(Family: Apiaceae) is considered to be one the most commonly used ethno-medicinal plants found in certain parts of Asian and European countries. These plants are known to exhibit therapeutic properties that can be used in the treatment of various health ailments such as acute infections, fever, throat infection, pneumonia, tonsillitis, diarrhea, hypertension, epilepsy, asthma etc. The main aim of the present study was to evaluate the antioxidant, anti-inflammatory, anti-diabetic and anti-microbial activity of leaf extracts of Eryngium foetidum. Phytochemical screening of methanol (ME), ethanol (EE), methanol: water (HME) and ethanol: water (HEE) extract of leaf tissue of E. foetidum was performed. The total phenolic and flavonoid content was found to be 0.205± 0.0015 mg GAE/g and 0.0345 ± 0.0015 mg QE/g FWt respectively. In vitro antioxidant capacity of hydromethanolic extract of E. foetidum by linear regression analysis was expressed as IC50 values and found to be 131.94 µg/ml and 195.6 μg/ml for DPPH radical scavenging and H2O2 scavenging respectively. The IC50 values for in vitro anti-inflammatory activities of the hydromethanolic extract of E. foetidum were evaluated by the following assays: heat induced protein denaturation (IC50 = 127.57µg/ml) and RBC membrane stabilization (IC50 = 225.32μg/ml) at different concentrations using aspirin as control. Studies were also carried out to assess the hypoglycaemic potential by assaying the ability of the plant to inhibit alpha amylase (IC50 = 442.0 μg/ml) and glucose diffusion. Antimicrobial activity of the extracts was studied against common pathogens. The zone of inhibition was observed by agar well diffusion method.