Vol. 5, Issue 2 (2020)
Phenolic compounds proliferation by HPLC: to find out antibacterial activities in Ficus benghalensis plant extract
Author(s): Tahreem Afzal, Qurban Ali, Arif Malik
Abstract: Ficus benghalensis belongs to family Moraceae were investigated for in vitro Anti-bacterial activity and phytochemical analysis. The present study demonstrates the anti-bacterial activity and anti-cancerous trend of tropical tree (Ficus benghalensis) on the foundation of area of hindrance. For finding the various bacterial strains to check its anti-bacterial activity of a Ficus species three different fractions of ethanol, methanol and aqueous also used by using agar disc diffusion method. Ficus benghalensis reveals hinderance at the range of 0.05mg to 0.2 mg in opposition to bacteria tested. Antimicrobial activity of Ficus benghalensis was determined by the calculated sample of leaf, roots and fruits. These extracts were used against the four types of bacteria Staphylococcus aureus, Escherichia coli, Pseudomonas protobacteria and Bacillus cereus. The higher growth inhibition zones were reported from roots and fruit samples extract of Ficus benghalensis. The HPLC analysis was used for the determination of phenolic compounds, secondary metabolites and their biochemical synthesis. It was found from results that large number of phytochemicals was present in the root and fruit extracts of the Ficus benghalensis. It was suggested from our study that the use of roots and fruits of Ficus benghalensis may be helpful to produce antibacterial medicines.