Bioactive properties, biosynthesis of silver nanoparticles of Wedelia chinensis and its applications

Keshav S Shinde; Sana Khan

Bioactive properties, biosynthesis of silver nanoparticles of Wedelia chinensis and its applications

Authors
Keshav S Shinde, Sana Khan

Abstract
The present investigation involves a study of bioactive substances from plant extracts of Wedelia chinensis. Plant phytochemicals contribute to great antimicrobial potential against bacterial cultures. Phytochemical analysis elucidated that Wedelia chinensis consist of a broad range of secondary metabolites including alkaloids, saponins, phenols, flavonoids, tannins, carbohydrates, terpenoids, glycosides, quinones, anti-oxidants. The antimicrobial activity of methanol extracts of Wedelia chinensis whole plant was studied by well diffusion method against ten bacterial cultures. The synergistic potential of leaf, stem and root extract was also studied and silver nanoparticles (NPs) were synthesized from the leaf, stem and root extracts. Cytotoxicity of the plant extracts and silver NPs was determined by brine shrimp lethality assay. The seed germination of silver NPs with Triticum seeds (wheat) was observed and found effective in seed germination. The obtained outcomes of the present study indicates that the extracts of Wedelia chinensis can be employed in the treatments of diseases caused by the test organisms along with the silver NPs which have wide range applications. Hence, Wedelia chinensis can be used to discern bioactive natural products and new pharmaceutical molecules that serve in the development of unmet therapeutic needs.

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