Antibacterial and phytochemical action of medicinal plant Peristrophe bicalculata against human pathogens

Dave S; Bhattacharya I; Das R; Agarwal S; Kumar A; Gangwane A K

Antibacterial and phytochemical action of medicinal plant Peristrophe bicalculata against human pathogens

Authors
Dave S, Bhattacharya I, Das R, Agarwal S, Kumar A, Gangwane A K

Abstract
The in vitro study of antimicrobial properties of peristrophe bicalculata was conducted using five different leaves extracts against five different human pathogens. Peristrophe bicalculata belong to the largest medicinal plant family acanthaceae and possess great value as a phytomedicine source. Positive results from antibacterial activity can prove these plant derived phytochemicals to be effective agents to be developed in phytomedicne in future which can overcome antibiotic resistance which is one the biggest threat in medical sciences. Peristrophe bicalculata showed maximum antibacterial activity in ethyl acetate solvent against selected human pathogens such as Escherichia coli, Streptococcus aureus and Bacillus subtilis. Different solvent systems were employed for extract preparation. For antibacterial activity agar well diffusion method was used and zone of inhibition measured. Thus, effective phytomedicine can be developed using Peristrophe bicalculata leaves extracts which can serve inordinate therapeutic value.

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