An improper use of agrochemicals especially fungicides which are more carcinogenic risk than insecticides and herbicides which gives rise to undesirable side effects. Natural fungicides were widely used in the perspective of sustainable methods of plant disease control because of their ecofriendly properties, being easily accessible and relatively less cost. The aim of the present work was to determine the in vitro antifungal activity of the aqueous leaf extracts of Tamarindus indica L., collected from Shendra M.I.D.C. area Aurangabad (MS).Their antifungal properties were tested against the five pathogenic fungi­­­- Fusarium incarnatum, Alternaria citri, Colletotrichum musae, Colletotrichum sp. and Gibberella avenaceum at different concentrations ranging from 10, 20, .....100%. At 100% concentration, aqueous leaf extract of Tamarindus indica L. shows excellent inhibitory activity against Alternaria citri (87.59%), Gibberella avenaceum (51.67%), Fusarium incarnatum (42.11%). The application of plant extracts for disease management could be less expensive, easily available, non- polluting and ecofriendly.