Nandur Madhyameshwar stream bank of Niphad Tehsil of Nasik district in order to assess some of the numerous medicinal plants present in the area. In totality nearly 27 species of plants have been recorded. Interviews were conducted with local people who reported medicinal uses. These uses are also supported from previous studies. We conclude that it is important to adopt conservation practices for sustainable plant use with and outside the study area in-view of the ecological function of the stream bank and the local therapeutic value of these plant resources.