Syzygium aromaticum (L.) is an important plant medicinal plant. It is a precious and valuable spices of the world. It is an unopened flower bud growing on a tree belonging to the family Myrtaceae. The present study involves comparative phytochemical analysis of leaves and buds of Syzygium aromaticum (L.). Phytochemical analysis of leaves shows that presence of alkaloids, flavonoids, phenols, tannins, terpenoids and glycosides in ethanolic, methanolic and aqueous extracts and Phytochemical analysis of buds shows that presence of alkaloids, flavonoids, phenols, tannins, terpenoids and glycosides in ethanolic, methanolic and aqueous extracts. Antibacterial activity done by agar well diffusion method. The antibacterial activity of both parts of plant showed positive results against E-coli but comparatively buds showed higher zone of inhibition as compare to leaves.