Medicinal plants have been an important source phytochemical, aromatic compounds etc. Gymnosperms used as ornamental purpose but nowadays most of the researchers are concentrate the isolation of active metabolites from many gymnosperms. In our present study to screen the phytochemicals and identify the active compounds through FTIR and GC-MS from the methanolic leaf extract of Cupressus. The active compounds were isolated from the leaf extract of Cupressus Geranyl tiglate, Oxirane, Caryophyllene, Humulene, β-copaene, Methanoazulene, Naphthalene, (+)-epi-Bicyclosesquiphellandrene, Cyclononene, 2-Piperidinone, acrylic acid, Phthalic acid, Androstan-17-ol, 1-Chloroeicosane, Tetratetracontane, Benzamide, Sandaracopimar-15-ene and Oxadiatzol. In the FTIR analysis to identified by the most important functional groups were noticed. There are 10 different functional groups were obtained such as esters, aromatic compounds, phenols, amines, aldehydes, ketons, halogens. Thus, the present study the proved that the Cupressus as a pool of secondary metabolites.