Plants have been associated with the life and culture of mankind since the beginning of the human civilization. India is exceptionally rich in rituals owing to its great diversity in religious cultures and traditions. Plants are considered as important components of these traditional rituals which are used for some definite purposes. A survey was conducted on some Hindu temples of Jajpur district of Odisha to explore the plants used in daily and festive rituals. The observations indicate that the present-day residents of Jajpur district of Odisha have been maintaining the age-old practice of offering of plants to the deities in form of fruits, flowers and leaves as well as specific floral objects during festivals and family rituals. The present communication attempts to document and enumerate the medico-botanical relevance of plants used in present-day religious rites by the people of Jajpur district of Odisha. During the survey 88 angiospermic species belonging to 74 genera and 43 families have been collected, critically studied, identified and incorporated in the Herbarium. Ailments covered in this paper include anorexia, bronchitis, cold, colic pain, conjunctivitis, constipation, diabetes, diarrhoea, dysentery, dysuria, epilepsy, galactorrhoea, menstrual disorder, piles, pyorrhoea, scabies, small pox, throat infection and foot and mouth disease in animals.