2061 species of higher spore, Gymnospermaceous and flowering plants belonging to 144 families and 764 genera have been established in the flora of the region. Herbariums based on a large number of collected plants were prepared and handed over to the Herbarium Found of the Institute of Botany of ANAS. 39 rare, endangered and 17 endemic plant species were identified. The stock of 40 species has decreased noticeably, 16 species are on the verge of extinction there, 5 species are under the threat of complete destruction and 17 species reduce their range in recent years. The composition and structure of the vegetation cover of the region under the influence of a complex of ecological, technogene, zoogenic and anthropogenic factors has changed greatly, where urgent measures for their improvement and protection are required for further use.