The effect of increasing concentrations (10, 20, 30, 40 and 50 mg kg-1) of soil cadmium on growth and biochemical contents in Sesuvium portulacastrum (L.), plants were analysed on 30^th, 60^th, 90^th, and 120th sampling days. Control plants were maintained separately. The inner surface of pots was lined with a polythene sheet. Each pot contained 3kg of air dried soil. Ten plant cuttings were planted in each pot. All pots were watered to field capacity daily. Plants were thinned to a maximum of six per pot, after a week of planting. Each treatment including the control was replicated five times. Cadmium at all levels (10, 30 and 50 mg kg-1) tested, decreased the growth parameters such as root and shoot length, and biochemical constituents such as, protein,(except, proline) and sugar contents in plants compared to untreated plants. The shoot length of cadmium treated Sesuvium portulacastrum (L.) plants was higher than the root length. When compared with proline content of root of Sesuvium portulacastrum (L.) plants was higher than shoot.