With deforestation, environmental pollution, un-restricted collection, genetic modification and all other kinds of human related measures together with climatic change, considerable amount of plants are under threat of eradicating from the world. Though in-situ conservation measures can be applied, ex-situ measures are more practical and efficient for the conservation of plant species. With continuously increasing technology, biotechnological approaches deliver some most promising methods for long term conservation of germplasms. In vitro conservation, cryopreservation and DNA storage techniques help to conserve plant genomes for a considerably long time. Objective of this review is to discuss the potential of conserving plant species through biotechnology.