Ethnobotanical field work is not the same as the normal field assortment, which are done typically by taxonomists or verdure authors. While taxonomist give accentuation on plants and their living space, the ethnobotanists, notwithstanding these angle, record the relationship of these plants with the neighborhood occupants. In this manner, the initial phase in ethnobotanical field work is to distinguish the nearby occupants or crude social orders and their local ward. Field concentrate in an ancestral territory gives direct data. Here the ethanobotanist separated from assortment of plant, likewise disks and records the employments of plants with the assistance of sources. Incredible persistence and diligence are needed in ethnobotanical study. Customarily utilized restorative plants have been a wellspring of alleviation in controlling different sorts of infections all through the globe. Ancestral individuals have customary information on plant species use for various purposes, for example, food, colors, gums, medication and so on. This paper reports an ethnobotanical study that focuses on the traditional medicinal plants used by local communities to treat human diseases. Ethnobotanical study of medicinal plants was carried out from June, 2017 to September 2019. The study is based on the documentation of medicinal plants used to treat various human diseases in the area. Ethnobotanical data were collected using semi structured interviews, group discussions with tribes, guided field walks, and observations with participants. The present paper reveals the study of 60 genera belonging to 37 families used by the tribes of Bhadradri Kothagudem district as well as Siddharthnagar district of Eastern Uttar Pradesh.