Jamun tree (Syzygium cumini L.) is a precious medicinal plant of the Myrtaceae family which has been used in the traditional medicine of India and the world. Geographical distribution and the botanical description has been reported in this review. Indian Black plum is extensively used in Ayurveda medicine, and it is used to cure cough, cold, asthma, allergic, inflammation and piles. The flower extract of this plant have antimicrobial activities and has about 10 mineral content in XRD analysis in various studies. The most important phytochemical studies of Jamun plum tree originated in 17th century. To date, about 35 components including cyanogenic glycoside, tannins, gallitannins, gallic acid, triterpenoids and essential oil have been extracted from different parts of the plant. With literature study, about the Jamun fruit is against 12 microbes with antimicrobial activity has been reported in the different parts of the black cherry. In general, the results of this study indicate that the Indian black cherry due to the effective phytochemical properties, antimicrobial, anti-inflammatory, antidiabetic, anticancer, anti Leishmaniasis, anti-obese Heptoprotective, Gastroprotective, anti-viral activities etc., it can be used to boost up the immune system treat of various diseases which can be used as an vital multi target therapeutic medicinal plant especially during this pandemic outbreak which battle against Covid-19 disease.