Colon cancer is extensive over the world. While ordinary anticancer therapies can support the influenced patients, cells of essential organs, for example, the kidney, lungs, bladder, and sensory system may experience the ill effects of symptoms of chemotherapeutic medications, with the goal that it is important to look for options. From old occasions, consideration has zeroed in on therapeutic plants and common items. The current examination investigated the cytotoxic impact of green tea and Black tea remove on human colon cancer HCT116 cells was surveyed by the MTT test. The HCT116 cells were treated with an expanding grouping of green tea and Black tea (25-300 µg/ml) for 24 h and the outcomes are communicated as a level of the control an incentive in introducing as a cell cytotoxicity proportion for HCT116 cells utilizing MTT measure. The IC50 of Green tea extricate uncovered by this cytotoxicity measure was around IC50 = 175.50µg/ml. The IC50 of Black tea remove uncovered by this cytotoxicity test was around IC50 = 220.50 µg/ml. The more prominent rate hindrance was seen in green tea when contrasted and Black tea in a portion subordinate way utilizing MTT test. This examination has featured the way that plant separates can go about as promising anticancer specialists, making them fitting segments to be applied for chemoprevention or malignant growth therapy. This investigation approves the conventional utilization of plants in the administration of the disease.