Many herbs recognized to have medicinal properties and many beneficial effects on health. Swertiachirata is one such herb, belonging to the family Gentianaceae, it also has many potential health benefits. It has been reported to have several pharmacological effect such as antimicrobial, anti-inflammatory, anti-cancer and analgesics. Humans from very long have been using traditional medicinal plants. Traditional plants play a very important role in preventing and treating of human diseases. Medicinal usage of Swertiachirata is reported in Indian pharmaceutical codex, the American and the British pharmacopoeias and in the different traditional systems of medicine (Unani, Ayurveda and Siddha). Swertiachirata is commonly known as a bitter tonic in the area of traditional medicine, due to the presence of many bioactive components, it tastes bitter but directly associated with human health welfare like used for the treatment of fever, loss of appetite, digestive disorders, diabetes, skin and various other diseases.