Cytotoxicity, antioxidant and antimicrobial assay of Elaeocarpus ganitrus (Rudraksha) seeds
Subhashish Tripathy, Amit Mishra, Arun Kumar Mishra
Objective: Pharmacological study of Rudraksha seed extract in Cytotoxicity, Antioxidant and Antimicrobial assay.Method: Cytotoxicity of the Rudraksha seed extract on HCT116 cell line established by MTT Assay. The total antioxidant activity test was performed with help of the phosphomolybdenum method. The antimicrobial activity was calculated by following the zone inhibition technique.Result: No significant Cytotoxicity was found in the extract up to 100μg/ml. The total antioxidant activity in 1 mg (1000 μg) extract is equivalent to 59.28 μg Ascorbic acid.The antimicrobial assay proves that Rudraksha seed extract has noteworthy antibacterial action against Staphylococcus Aureus bacteria.Conclusion: These scientific researchers agree on the traditional use of Rudraksha seed for medicinal use.