Phytochemical analysis, antioxidant and antibacterial properties of Opuntia Ficus-indica (L.) mill.against the wound infecting bacteria
G Malathi, Arul Kumar Murugesan
Oxidative stress is initially generated by free radicals which makes electrons to paired with biological macromolecules in cells of healthy humans and induce DNA and protein damage. Infectious diseases are still a major threat to the public health despite of enormous development in the medical field. Nowadays various synthetic drugs became resistant to various infectious diseases. Therefore, various phytochemicals in medicinal plants are in use for the treatment of several oxidative stress related disease. In the present study, Cactus Pear was selected to analyze the phytoconstituents using aqueous extract. Phytochemicals like phenols, flavonoids, alkaloids, tannin, saponin and glycosides was observed in aqueous extract of Cactus pears. Total flavonoids and phenolics content was also evaluated by aluminum chloride method and Folin’s Ciocalteau methods respectively. Antioxidant and radical scavenging efficiency was evaluated by reducing power assay and hydroxyl radical scavenging assay. An excellent reducing potential and radical scavenging activity was observed in aqueous extract of Cactus pear. Finally efficiency of Cactus pear against the growth of Methicillin Resistant Staphylococcus aureus (MRSA)from clinical isolates was evaluated. Aqueous extract of Opuntia ficus-indica exhibited excellent efficiency in anti-staphylococcal activity. Hence, based on the above studies, we could confirm that, O. ficus-indica could be used as a potential drug for the treatment of oxidative stress related diseases.