ARCHIVES
VOL. 6, ISSUE 5 (2021)
Preliminary profile of pharmacognostical and pharmaceutical analysis of Laghusutashekhara rasa tablet prepared by the method of Panchabhautika chikitsa- An ayurvedic herbo-mineral formulation
Authors
Ashvinee Vasava, Shubhangi Kamble, C R Harisha, V J Shukla, A S Baghel, Hitesh A Vyas
Abstract
Background: Laghusutshekhara Rasa (LSSR) is very popular formulation consisting of one herbal drug and one mineral drug which had been mentioned in the context of treatment of gastrointestinal tract disorders in different classical texts of Ayurveda. The classical composition of LSSR is having three contents but the yoga which has been used in present study is different from it. The present yoga of LSSR has been adopted from the famous Panchabhautika Chikitsa Paddhati which is very popular and being used by many practitioners in their daily practice. This is an Anubhuta Yoga (experiential formulation), which is having different contents, their proportions and method of preparation than that of classical yoga. Even though the dosage form of vati had been suggested for this formulation in classics, but for proper dose fixation it was converted in tablet form. Hence the need regarding its pharmacognostical and pharmaceutical analysis was felt for its standardization purpose. Aim: To develop preliminary profile of pharmacognostical and pharmaceutical analysis of Laghusutashekhara Rasa tablet prepared by the method of Panchabhautika Chikitsa. Methods: The LSSR tablet was subjected to macroscopic study, organoleptic parameters and microscopic study for pharmacognostical evaluation. Physico-chemical analysis like weight variation, tablet disintegration time, tablet hardness, loss on drying, ash value, acid insoluble ash, iron content, water and methanol soluble extracts, pH value along with high performance thin layer chromatography (HPTLC) were carried out for pharmaceutical evaluation. Results: Pharmacognostical study showed the presence of certain diagnostic characters of LSSR, ingredients in the formulation like fibres coated with Gairika, scalariform vessels coated with Gairika, starch grains coated with Gairika etc. Preliminary physico-chemical analysis showed that hardness of tablet 1 kg/cm2, tablet disintegration time 1 minute, ash value 37.556% w/w, loss on drying 4.908 % w/w, water and methanol soluble extracts as 8.86 % w/w and 3.785% w/w respectively, acid insoluble ash 15.69 % w/w and pH value 5.5. HPTLC showed fifteen spots at 254nm and fifteen spots at 366nm. Conclusion: The study was carried out to standardize the finished product Laghusutashekhara Rasa tablet in terms of its identity, quality and purity. Pharmacognostical and physico-chemical observations revealed the specific characters of all active constituents in the preparation. This preliminary profile of Laghusutashekhara Rasa tablet may prove beneficial for its further standardization.
Download
Pages:813-818
How to cite this article:
Ashvinee Vasava, Shubhangi Kamble, C R Harisha, V J Shukla, A S Baghel, Hitesh A Vyas "Preliminary profile of pharmacognostical and pharmaceutical analysis of <em>Laghusutashekhara</em> <em>rasa</em> tablet prepared by the method of <em>Panchabhautika chikitsa</em>- An ayurvedic herbo-mineral formulation ". International Journal of Botany Studies, Vol 6, Issue 5, 2021, Pages 813-818
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.