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VOL. 6, ISSUE 5 (2021)
Evaluation of in vitro antimitotic activity of Ocimum basilicum leaves extract
Authors
Shibula K, Amargeetha A, Shalini R, Suriya P
Abstract
Plants are rich sources of secondary metabolites with interesting biological activities. The occurrence of cancer is due to the effect of chemicals, viruses, free radicals and some environmental and routine life factors. Traditional treatments for cancer like chemotherapy, radiotherapy and surgery provide only partial and transient relief. Also the above treatments and synthetic anticancer drugs are costly and beyond the reach of the general public. Hence, alternative herbal remedies that are commonly available and comparatively economical are to be explored. The antimitotic and antiproliferative effects are the important In vitro assays for the screening of anticancer compounds. In the present study to investigate the phytochemical screening and antimitotic activities of Ocimum basilicum leaves. The phytochemical screening Ocimum basilicum leaves showed that the presence of saponins, flavonoids, steroids, terpenoids, triterpenoids, anthroquinones, polyphenol, and coumarins in both extracts, significant amount of phenol (133.14mg/gm), flavonoids (25.33mg/gm) and terpenoids (10.72mg/gm). The histochemical analysis further confirmed in the presence of saponins, flavonoids, tannins, terpenoids and polyphenol. The extract of Ocimum basilicum leaves had excellent anti-mitotic activity. Overall, it concluded that the extract of Ocimum basilicum leaves has rich source of phytochemicals and anti-mitotic activity proved by Allium assay.
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Pages:840-845
How to cite this article:
Shibula K, Amargeetha A, Shalini R, Suriya P "Evaluation of <em>in vitro</em> antimitotic activity of <em>Ocimum basilicum </em>leaves extract ". International Journal of Botany Studies, Vol 6, Issue 5, 2021, Pages 840-845
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