Over the centuries, herbal drugs have been used as major sources of medicine for the prevention and treatment of diseases. Based on the origin of material, Ayurvedic medicines are divided into 3 categories, particularly plants, mineral and animal. Among this, herbal formulation has gained nice importance and rising international attention recently. In recent years, there has been an exponential growth in the field of herbal medicines and these drugs are gaining popularity both in developing and developed countries because of their natural origin and less side effects. Polyherbal drugs have more advantage when compared with the individual form. Polyherbal drug also creates some problems. Diabetes mellitus requiring a multipronged therapeutic approach. There are numerous herbs have been recommended for treatment of diabetes. In the current scenario, the use of polyherbals is increasing among the diabetics. Polyherbal formulation shows additional effect on diabetes compared with single herbal drug.