ARCHIVES
VOL. 6, ISSUE 5 (2021)
Effect on anti-diabetic and antibacterial activities of polyphenol rich extract from the seeds of Caesalpinia crista
Authors
D Amirtharaj, R Sivashankar
Abstract
The aim of this study was to evaluate the antidiabetic and antibacterial, polyphenol rich extract from the seeds of Caesalpinia crista. Phytochemicals were studied through qualitative tests and phytochemical visualized by thin layer chromatography (TLC). Polyphenol rich extract from the seeds of C. crista were assessed for antibacterial potential via the agar well diffusion method against Staphylococcus aureus, Escherichia coli, Enterococcus faecalis and Pseudomonas aeruginosa. The minimal inhibitory concentrations (MIC) were determined by the microdilution method. In vitro antidiabetic activity of the polyphenol rich extract from the seeds of C. crista was considered using inhibition of amylase and glucosidase assays. Polyphenol rich extract from the seeds of C. crista had the highest phenolic and flavonoid contents (66.78±1,89 µg GAE/g, 54,56±2.84µg QE/g. Polyphenol rich extract from the seeds of C. crista considerably inhibited the growth of the bacteria S. aureus, E. coli and K. pneumonia. The lowest EC50 value (76.32 and 71.32 μg/mL) observed in the inhibition of amylase and glucosidase. The study therefore showed that the polyphenol rich extract from the seeds of C. crista possess significant antibacterial and inhibitory effect on glucose diffusion in vitro thus affirming the traditional claim of the use of plant in treating bacterial Infection and diabetes.
Download
Pages:616-621
How to cite this article:
D Amirtharaj, R Sivashankar "Effect on anti-diabetic and antibacterial activities of polyphenol rich extract from the seeds of <em>Caesalpinia crista</em> ". International Journal of Botany Studies, Vol 6, Issue 5, 2021, Pages 616-621
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.