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VOL. 6, ISSUE 5 (2021)
Effect on anti-diabetic and antioxidant activities of flavonoid rich extract from the leaves of Aegle marmelos
Authors
R Sathyaseela, S Tamilselvi
Abstract
The aim of this study was to evaluate the anti-diabetic and antioxidant, phytochemical composition of flavonoid rich extract from the leaves of A. marmelos. Phytochemicals were analyzed through chemical tests, thin layer chromatography (TLC). Flavonoid rich extract from the leaves of A. marmelos were evaluated for antidiabetic potential via the inhibition of amylase and glucosidase. In vitro antioxidant activity of the flavonoid rich extract from the leaves of A. marmelos was evaluated using ABTS, inhibition of lipid peroxidation and metal chelating. Flavonoid rich extract from the leaves of A. marmelos had the highest phenolic and flavonoid contents (71.32±2.34 µg GAE/g, 59.32±0.25 µg QE/g. In vitro antioxidant potential at a concentration of 100 μg/mL of flavonoid rich extract from the leaves of A. marmelos. The lowest EC50 (66.32 and 69.32 μg/mL) observed in the ABTS scavenging and inhibition of lipid peroxidation. Positive correlations were observed between total phenolics, antidiabetic and antioxidant potential of the flavonoid rich extract from the leaves of A. marmelos, indicating a significant contribution of flavonoid compounds.
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Pages:603-608
How to cite this article:
R Sathyaseela, S Tamilselvi "Effect on anti-diabetic and antioxidant activities of flavonoid rich extract from the leaves of <em>Aegle marmelos</em> ". International Journal of Botany Studies, Vol 6, Issue 5, 2021, Pages 603-608
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