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VOL. 6, ISSUE 6 (2021)
Pharmacological review on alzheimer’s diseases
Authors
V Gomathi, V Abinash, M Bharathkumar, S Jairamnath, K M Muhammadazarudeen, Ma Muhammad Parvez Mushraf
Abstract
In 2013, 44 million of the world-wide population was estimated to be affected by dementia and a steep rise to ~136 million has been predicted by 2050. To date, there are no treatments with proven disease-modifying effects and AD remains the largest unmet medical need in neurology.AD pathology presents a complex interplay between several biochemical alterations, including changes in amyloid precursor protein metabolism, phosphorylation of the tau protein, oxidative stress, impaired energetics, mitochondrial dysfunction, inflammation, membrane lipid dysregulation and neurotransmitter pathway disruption.It undergoes the anatomy of the alzheimer’s diseases. Whereas these observes the changes in the brain and also the epidiomiology of alzheimer’s diseases.It explains in detail about the etiology of alzheimer’s may includes genetic causes,advancing age,family history and hypertension.These also includes three different phases.These undergoes with the pathophysiology,signs and symptoms as well as the diagnosis of the disease,. Pharmacotherapy and the symptomatic treatments of the disease may also involved.Finally it overcomes the future directions of the alzheimer’s disease.
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Pages:305-313
How to cite this article:
V Gomathi, V Abinash, M Bharathkumar, S Jairamnath, K M Muhammadazarudeen, Ma Muhammad Parvez Mushraf "Pharmacological review on alzheimer’s diseases ". International Journal of Botany Studies, Vol 6, Issue 6, 2021, Pages 305-313
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