Tomato (Solanum lycopersicum L.) belongs to the Solanaceae family and is the second most important horticultural product cultivated worldwide. Because of its importance as food, tomato has been bred to improve productivity, fruit quality, and resistance to biotic and abiotic stresses. Tomato has been widely used not only as food, but also as research material. The tomato plant has many interesting features such as fleshy fruit, a sympodial shoot, and compound leaves, which other model plants (e.g., rice and Arabidopsis) do not have. Field experiments were conducted in a private farm in East Godavari district, Andhra Pradesh to evaluate the efficacy of ten chemical fungicides against Fusarium wilt disease under field conditions during the two consecutive seasons (2018-2019 and 2019-2020). Each fungicide and bio fungicide was applied at two rates as foliar spraying 3 times per season. These results revealed that Tebuconzole + Trifloxystrobin completely inhibited growth of Fol, at 1000 ppm.