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VOL. 6, ISSUE 6 (2021)
in vitro pancreatic lipase inhibition potential of commonly used Dioscorea species
Authors
Ruturaj S Patil, Mahesh P Mane, Aditya B Magdum, Mansingraj S Nimbalkar
Abstract
To minimize energy intake through gastrointestinal pathways, the production of nutrient digestion and absorption inhibitors is considered as an essential strategy among the current treatments for obesity. Pancreatic lipase is one of the key enzymes, which act on the dietary fat and help in absorption of dietary fat. Inhibition of the lipase enzyme helps in the reduction of fat absorption and obesity management. The extracts of four different Dioscorea species were screened for Primary phytochemicals like phenolic, flavonoids highest phenolic content was found in D. alata dry root methanolic extract and flavonoids was found in D pentaphylla dry aerial part extract. Different plant part extracts in different solvent were assessed for the lipase inhibition activity. The highest activity was observed in D pentaphylla aqueous extract of dry aerial part 76.71±0.024% with IC50 value 0.850mg/gm. The activity differs with different solvent and plant parts. Dioscorea species exhibit strong lipase inhibition potential hence can be used for the obesity management.
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Pages:1107-1110
How to cite this article:
Ruturaj S Patil, Mahesh P Mane, Aditya B Magdum, Mansingraj S Nimbalkar "<em>in vitro</em> pancreatic lipase inhibition potential of commonly used <em>Dioscorea</em> species ". International Journal of Botany Studies, Vol 6, Issue 6, 2021, Pages 1107-1110
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