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VOL. 6, ISSUE 6 (2021)
Evaluation of antioxidant and pancreatic lipase inhibitory potential of Polygala glaucoides L. and Polygala erioptera DC
Authors
Mahesh P Mane, Ruturaj S Patil, Aditya B Magdum, Chirag U Narayankar, Mansingraj S Nimbalkar
Abstract
Obesity is the accumulation of abnormal or excessive fat that might make it difficult to maintain a healthy weight. Polygala glaucoides L and Polygala erioptera DC extracts were evaluated for their anti-pancreatic lipase and antioxidant activity. DPPH, ABTS, and ferric-reducing antioxidant power assays were used to determine the extracts' antioxidant activity. The leaf extract showed highest antioxidant potential for all three studied antioxidant assays in P. glaucoides whereas in P. erioptera stem has the highest antioxidant capacity. All extracts were found to inhibit pancreatic lipase activity, but among all extracts leaf showed maximum inhibitory potential for lipase i.e., 84.99 ±0.021 % in P. glaucoides and 74.59 ±0.02% in P. erioptera. The standard drug orlistat having 68.25 ±0.002% inhibitory activity for lipase. Plant extracts are showing more inhibitory activity for lipase as that of orlistat. In both the studied activities leaf extract showed more potential indicating it has compounds that can be used to treat obesity related to inflammation and oxidative stress.
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Pages:1259-1264
How to cite this article:
Mahesh P Mane, Ruturaj S Patil, Aditya B Magdum, Chirag U Narayankar, Mansingraj S Nimbalkar "Evaluation of antioxidant and pancreatic lipase inhibitory potential of <em>Polygala glaucoides </em>L. and <em>Polygala erioptera </em>DC ". International Journal of Botany Studies, Vol 6, Issue 6, 2021, Pages 1259-1264
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