Anisomeles malabarica is a perennial herbaceous shrub. To test cell viability, breast cancer cells (MCF 7) were treated with different doses of plant leaves extract and known standard compounds including cis -vaccenic acid and linoleic acid. The cells were analyzed after 24 hours treatment and notable morphological changes were observed. Treated cells were showing drastic morphological changes such as rounding up of cells, connection and contact were lost with adjacent cells and observed to be easily detachable from the dish. It is a remarkable evident that it can be used as alternate source of medicine in the breast cancer treatment.