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VOL. 6, ISSUE 6 (2021)
Evaluation of in-vitro anthelmintic potential of various extracts of emblica officinalis
Authors
Padmaja Kore, Rashmi Tantri, Anuradha More, Shweta Ghodke, Sheetal Chaudhari
Abstract
Objective: The present study was aimed to evaluate the in-vitro anthelmintic potential of Emblica officinalis (Indian gooseberry) against Pheretima Posthuma (Indian earthworm). Methods: Different extracts of Emblica officinalis as methanolic, ethanolic and hydroalcoholic were prepared and used in different concentrationssuch as10, 20 and 30 mg/ml with normal saline were used in the study. The worms were randomized in to 11 groups of six worms each (of similar type). Piperazine citrate (10 mg/ml) was used as a reference standard. For each worm paralysis time and death time was observed. When there was no movement observed except for when the worm was shaken vigorously, paralysis (P) in min was noted andwith confirmation of lack of movement even when the worm was shaken vigorously as well as when dipped in warm water (50o C), death time (D) in min was recorded. Results: In all the extracts, worms were paralyzed and death occurred in a dose dependent manner. The hydroalcoholic extract was proven as most potent amongst all the extracts. Conclusion: Emblica officinalis can be used as a potential herbal remedy for the treatment of helminths infection.
Pages:1507-1514
How to cite this article:
Padmaja Kore, Rashmi Tantri, Anuradha More, Shweta Ghodke, Sheetal Chaudhari "Evaluation of <em>in-vitro</em> anthelmintic potential of various extracts of emblica officinalis ". International Journal of Botany Studies, Vol 6, Issue 6, 2021, Pages 1507-1514
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