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VOL. 6, ISSUE 6 (2021)
Isolation, characterization and phytochemical evaluation of active compound lupeol from Stobilanthes ciliatus nees
Authors
John Thomas, M V Kumudhavalli
Abstract
Medicinal plants have served through ages, as a constant source of medicaments for the exposure of a variety of diseases. Plants are known to provide cures for various human illnesses and are a rich source of phytoconstituents having diversified pharmacological properties. In recent years the use of medicinal plant has increased as a low cost alternative to the expensive modern drugs. Strobilanthes ciliatus Nees (Bremek) Known as “Sahachara” is widely used today in indigenous Indian systems of medicine has been shown to possess a range of folk and proven biological activities such as anti-inflammatory, analgesic, anticancer, antimicrobial, antidiabetic and hepatoprotective. The roots and leaves of the plant are used as major ingredient in many of the ayurvedic preparations especially meant to relieve pain and inflammation Compounds such as lupeol, stigmasterol, betulin, stigmasterol glycosides and 4- acetyl-2, 7-hydroxy-1, 4, 8,-triphenyl-octane-3, 5-dione were reported from the acetone extract of the stem. Lupeol is the major compound reports from the various parts of the plant and is well reported for its broad pharmacological potential. The present aim of the study is to extraction and isolation of bioactive compound from Strobilanthes ciliatus (Bremek.). The isolation and characterization analysis included, Thin Layer Chromatography, High Performance Thin Layer Chromatography, GC-MS and Spectroscopy studies (IR, NMR, and MASS). The presences of Lupeol in the methanolic fraction revealed that the isolated constituent is most active compound. Isolation of bioactive compound Lupeol may help in identification of various pharmacological activities and carrying out further research in Strobilanthes ciliatus (Bremek).
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Pages:485-491
How to cite this article:
John Thomas, M V Kumudhavalli "Isolation, characterization and phytochemical evaluation of active compound lupeol from <em>Stobilanthes ciliatus </em>nees ". International Journal of Botany Studies, Vol 6, Issue 6, 2021, Pages 485-491
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