The name Onosma was making known to into contemporary botanical vocabulary by Linnaeus, it was derived from a Latin word “osma” coined from a Greek word, “osma” (smell). The Boraginaceae is the family name for Onosma bracteatum Wall. It is recognised as Gaozaban in the ancient unani system of medicine and as Sedge in the Middle East. O. bracteatum is commonly used as a demulcent, alterative, diuretic, immunity enhancer and spasmolytic and as a major constituent of various ayurvedic formulations for the treatment of hypertension, leprosy, rheumatism and asthma. The Pharmacognostic investigations carried out on plant till date are not sufficient. Thus the present study includes detailed investigation of leaves of Onosma bracteatum using macroscopy, microscopy, physiochemical, phytochemical parameters and fluorescence analysis. The study also involves qualitative and quantitative estimation of some metabolites. The overall outcome of this detailed study will be helpful in proper identification, evaluation and grounding of a monograph of O. bracteatum.