International Journal of Botany Studies

International Journal of Botany Studies


International Journal of Botany Studies
International Journal of Botany Studies
Vol. 7, Issue 1 (2022)

Antibacterial, antioxidant potential and functional group analysis of Kashmir grown Prunella vulgaris L. root extract


Khursheed Ahmad Dar, S Senthilmurugan, A Venkatesan

The root of Prunella vulgaris (Lamiaceae), was investigated for its in vitro anti-oxidant and anti-bacterial activity. The antioxidant activity revealed that the methanol extract of Prunella vulgaris root (MERE) possess highest scavenging capacity than petroleum ether extract (petroleum ether = PERE). The antimicrobial activity showed that Staphylococcus aureus, Klebisiella pneumonia and Escherichia coli were the most susceptible pathogens and significant activity was also recorded by PERE against Staphylococcus aureus, S. pneumonia, Enterococcus faecalis and K. pneumonia strains tested, at different concentrations. Column chromatographic fractions were also tested for antibacterial activity, wherein F4 (fraction 4) out of six fractions showed appreciable antibiotic activity against all the organisms tested. FT-IR analysis was done to confirm functional groups and nutrient type present. Besides the plant has great importance as far as its other clinical applications are concerned. The present investigation can be used for comparative evaluation of bioactive constituents with other species of medicinal plants present in different parts of the world and can be used for preparation of superior combination of this herb to use in pharmaceutical industries.
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How to cite this article:
Khursheed Ahmad Dar, S Senthilmurugan, A Venkatesan. Antibacterial, antioxidant potential and functional group analysis of Kashmir grown Prunella vulgaris L. root extract. International Journal of Botany Studies, Volume 7, Issue 1, 2022, Pages 19-25
International Journal of Botany Studies International Journal of Botany Studies