Thujopsis dolabrata, a monoecious coniferous tree, have its place in the Cupressaceae family. The plant with terrestrial habitat and evergreen leaf sheddability is native to Japan and for environmental stress factors got distributed to wider locations. This current review abridges the detailed information about the properties of the compounds extracted from this plant and the research work carried out on it in order to offer updated information that could be beneficial for the future exploitation of the plant. The review summarizes the bioactivity and the chemical identity of T. dolabrata studied by various researchers from 1965 to till date. Due to the availability of this plant in India, other than Japan, makes it convenient to carry out more studies and experiments on the subject. In fact, the lack of any scientific study on the plant reported from India makes it further more significant and opens up the scope for substantial new findings. The review also seeks the possibility of biotransformation of T. dolabrata, by a bacterial or a fungal agent, which may alter the chemical constituents present in the plant for enhanced or novel beneficial activities.