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VOL. 7, ISSUE 1 (2022)
Assesment of serum protein and hepatic marker enzyme profiles of diabetic Albino mice treated with glibenclamide and leaf methanolic extract of Syzygium caryophyllatum (L.) Alston
Authors
Savitha Rabeque C, S Padmavathy
Abstract
Diabetes mellitus, once considered a disease of minor significance to world health, is now a major threat to human health in the 21st century. Several hypoglycemic agents have been reported to produce serious adverse side effects such as liver problems, lactic acidosis and diarrhea. So the present study was aimed to investigate the effect of leaf methanolic extract of Syzygium caryophyllatum (L.) on liver and kidney function on alloxan induced diabetic mice. The result indicated that a significant reduction in serum protein, albumin and globulin and in the elevation of SGPT and SGOT levels in alloxan induced diabetic group (Group II), when compared to control (Group I) and glibenclamide treated mice (Group III). On administration of methanol leaf extracts of S caryophyllatum to the diabetic group restored the level of protein, albumin and globulin and liver marker enzymes levels.
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Pages:667-671
How to cite this article:
Savitha Rabeque C, S Padmavathy "Assesment of serum protein and hepatic marker enzyme profiles of diabetic Albino mice treated with glibenclamide and leaf methanolic extract of <em>Syzygium caryophyllatum</em> (L.) Alston ". International Journal of Botany Studies, Vol 7, Issue 1, 2022, Pages 667-671
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