International Journal of Botany Studies

International Journal of Botany Studies


International Journal of Botany Studies
International Journal of Botany Studies
Vol. 7, Issue 1 (2022)

GC-MS, antibacterial and antioxidant potential of Leucas lavandulifolia Sm


Periasamy Sakthidhasan, Jayaraman Banupriya, Ramasamy Rajesh, Madepalli Byrappa Gowdu Viswanathan

Leucas lavandulifolia Sm. belonging to Lamiaceae is used extensively to treat various diseases in traditional medicine. Our aim of investigation to analysis the present of compounds and estimate the antioxidant and antibacterial activity of L. lavandulifolia floral extracts. Floral powder was successively extracted with various organic solvents in the order of increasing polarity, analysed for phytochemical constitution through GC-MS analysis. Screened for antioxidant activity DPPH and Ferric reducing ability and antibacterial activity was analysis by well diffusion methods. GC-MS analysis showed Tetracontane, Phenol, 2,4-bis(1,1-dimethylethyl)-, 5,7-dodecadiyn-1,12-diol and other 36 compounds. DPPH assay expressed IC50 values in the order of methanolic floral extract, ascorbic acid, ethyl acetate, chloroform and petroleum ether floral extracts such as 3.91, 0.24, 6.13, 5.38 and 69.75 μg/ml respectively. FRAP assay exhibited methanol floral extract and ascorbic acid respectively showed 0.2641 and 2.0088 (32 µg/ml). Methanol floral extract at 100 µg/ml concentration exhibited 17 mm (Aeromonas hydrophila), 18 mm (Pseudomonas aeruginosa), 19 mm (Aeromonas caviae), 20 mm each (Klebsiella pneumoniae and Streptococcus pyogenes), 21 mm each (Enterococcus faecalis and Enterobacter aerogenes), 22 mm each (Salmonella typhi and Corynebacterium diphtheriae) and 23 mm against Proteus mirabilis. In this present study of plant species showed the present of biologically valuable secondary metabolites deducted by GC-MS analysis. It had strong antioxidant activity and exposed the significant antibacterial activity in methanolic extract. Further studies on the isolation and characterization of various bioactive principles from this herb as a potential source of natural antimicrobial agents will thereby be motivationally considered.
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How to cite this article:
Periasamy Sakthidhasan, Jayaraman Banupriya, Ramasamy Rajesh, Madepalli Byrappa Gowdu Viswanathan. GC-MS, antibacterial and antioxidant potential of Leucas lavandulifolia Sm. International Journal of Botany Studies, Volume 7, Issue 1, 2022, Pages 264-269
International Journal of Botany Studies International Journal of Botany Studies