Effects of Dioscorea bulbifera nutritional potential on in vitro anti-inflammatory and anti-obesity properties: Tamilnadu's unconventional food plant
T Thiyagasundaram, Sivashankar Rangasamy
Objective: Obesity-induced chronic inflammation has been combated with dietary methods that include structured lipids such as medium-chain fatty acids and diacylglycerols. Obesity is indeed a multifaceted condition that results to a variety of life-threatening disorders. It is quickly becoming one of the most potentially serious issues, with significant economic repercussions.Methods: Obesity is on the rise at an alarming rate, so finding natural products that can help people lose weight while having the fewest adverse effects has been more important. One of the most commonly investigated techniques for determining the potential efficacy of anti-obesity agents is the inhibition of digestive enzymes. Using two complementary methods: ABTS radical scavenging activity and iron reducing power tests, complete aqueous extracts of Dioscorea bulbifera were evaluated for inhibitory activity against pancreatic lipase, lipoxygenase, and protein denaturation, as well as for anti-oxidant potential, using two complementary methods: ABTS radical scavenging activity and iron reducing power assays.Results: The total phenolic and flavonoid content of Dioscorea bulbifera aqueous extracts was also calculated quantitatively. The results revealed that Dioscorea bulbifera aqueous extracts were the most active plants Inhibition of lipase 64.23%, lipoxygenase inhibition 81.23% and albumin denaturation 82.31%.Conclusion: As a result, the current study reveals that aqueous extracts of Dioscorea bulbifera could be useful in the treatment of obesity.
T Thiyagasundaram, Sivashankar Rangasamy. Effects of Dioscorea bulbifera nutritional potential on in vitro anti-inflammatory and anti-obesity properties: Tamilnadu's unconventional food plant. International Journal of Botany Studies, Volume 7, Issue 1, 2022, Pages 472-478