Ethnobotany is the study of plants which are being used by tribal people to treat various diseases. In the present investigation, on the basis of tribal knowledge, we collected 10 ethnobotanical plants of various families (Azadiracta indica A. Juss, Calotropis procera, Ricinus communis, Withania somnifera, Argemone maxicana, Oscimum sanctum, Hemidesmus indicus L., Abrus precatorius, Hygrophila auriculata, and Vitex negundo). Plant parts used as traditional therapeutic purpose were selected for the study. Primary metabolites (TSS, proteins, free amino acids, and lipids) and secondary metabolites (total phenolic compounds, flavonoids, alkaloids, tannins, terpenoids, saponins) were determined quantitatively by using standard methods. Results revealed that these plant parts were rich in these metabolites. So, it can be concluded that the medicinal properties of these plant parts are due to presence of important phytochemicals.