World is affected by so many diseases, and the diseases cure by some of the treatments, but some of the diseases there is no proper treatment in that one of the diseases that affecting our largest part of human body is skin affected due to some antigen and antibody reaction, increases the keratinocyte proliferation, progression of T-cells and cytokines leads to the silver scales and itchy, it is psoriasis, it is one of the disease that affecting many population due to genetic and external factors, but there is no proper treatment of psoriasis, but some of topical, systemic treatments but there is severe adverse effects. But in our ancient treatment in Ayurveda, Siddha, Unani, using some of herbals to treat psoriasis by inhibiting keratinocyte proliferation and high wound healing of plant possess those characteristics.