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VOL. 7, ISSUE 2 (2022)
Formulation and evaluation of combined herbal tablet of S. Oblonga linn. and E. Littorale blume. extract
Authors
Sanjiv Duggal, Sanjeev Mittal
Abstract
The aim of the current study was to prepare Combined Herbal Tablet (CHT) from Indian Medicinal Plants whole extracts of S. oblonga Linn. stem and E. littorale Blume. aerial part. The plants were selected based on extensive literature review, which reflect their utility in treatment of diabetic patients. Wet granulation technique were used for formulation of CHT and assessed according to the Pharmacopoeial guidelines. The preformulation investigation of CHT demonstrated that all the results were within adequate limit. Friability and hardness are important characteristics for disintegration of tablet. Result of the present study had showed hardness of CHT range from 4.78±0.71 to 5.73±0.96 and whereas, %friability ranges from 0.34±0.011 to 0.88±0.074, indicated that the CHT were mechanically stable. CHT granules displayed excellent to good flow and were compacted into 460 mg tablets. The weight variation test of herbal tablet was passed (mean weight- 468 mg, weight variation ≤ 5% as per USP). The disintegration time range of CHT was 13.29±1.88 to 21.02±2.65. The last end drawn from the previously mentioned information is that the conceivable utilization of this economical natural formulation of plant origin might additionally be investigated for antidiabetic potential along with mechanism of action and its long term safety.
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Pages:436-441
How to cite this article:
Sanjiv Duggal, Sanjeev Mittal "Formulation and evaluation of combined herbal tablet of <em>S. Oblonga linn</em>. and <em>E. Littorale blume</em>. extract ". International Journal of Botany Studies, Vol 7, Issue 2, 2022, Pages 436-441
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