This paper represents the survey of medicinal plants available in Pandharpur tehsil on the bank of Bhima River and territory. This investigation carried out in 2018 -2021, through several field visits and interviews. In present work the total 105 species belongs to 50 families were found which are used as traditional medicine for the treatment of various ailments. Used on frequently occurs in human life such as rheumatism, cough, fever, snake bite, wounds. In the study area most commonly used highly medicinal plants such as Azadirachta indica, Bacopa monnieri, Ricinus communis, Tinospora cordifolia, Tridax procumbaens, Withania somnifera. This traditional knowledge is a treasure for world to challenge chemical side effects.