Phytochemicals are bioactive compounds present in plants, provide nutritional benefits and reduce the risk of major chronic diseases. Screening of the phytochemicals is the pioneer step in drug discovery. This study aims to evaluate the antimicrobial activity of aqueous, chloroform, and ethanol extracts of Moringa oleifera and Citrus maxima medicinal plants against two Gram-positive bacteria and two Gram-negative bacteria using phytochemical analysis. In the study, it was revealed that plants with phytochemicals show significant antibacterial activity.