The present study compares leaf morphological variations among twenty cultivars of betel from Kerala. There are over 100 different types of betel cultivars in the world and depending upon the area of cultivation they shows variation in taste and smell. Morphological study revealed significant differences among the cultivars in both qualitative (Colour of lamina, leaf apex shape, lamina orientation along the midrib etc) and quantitative characters (leaf length, width, Length of petiole, depth of sinus, width of lobe, etc.). The comparative morphological assessment cultivars revealed that Karpooram, Selan and Thulasi, show remarkable similarity among them compare to that of the rest of cultivars.