In order to determine the effectiveness of Chromolaena odorata on the production performance of three kinds of Abelmoschus esculentus, namely HIRE, SAHARI F1, and KIRIKOU F1, greenhouse research were carried out. The studies were set up using a Split Plot Completely Randomized Design (CRD) with six treatments and four duplicates for each treatment. On the germination rate, plant height, number of leaves, leaf area, weight of fruits, number of seeds, length of longest root, fresh weight, dry weight, moisture content, and physicochemical characteristics of the soil, the impacts of various treatments were assessed. Analysis of Variance (ANOVA) was used to examine the data in order to determine whether the difference was significant at (p0.05). According to the study, Chromolaena odorata application changed the chemical properties of the soil, resulting in compost that was fertile enough for Abelmoschus esculentus. Following KIRIKOU F1 and HIRE, Chromolaena odorata exhibited the most stimulating effect on the development performances of variety SAHARI F1. Thus, given its economic significance as a green manure in Nigeria, this study suggests using Chromolaena odorata in farming techniques.