Weeds are one of the plant-disturbing organisms that are an obstacle in lowland rice cultivation in Indonesia because they can cause competition for nutrients, light, water, and space to grow. Herbicides are considered more effective in controlling weed populations in a relatively short time and covering large areas. One herbicide that can be used to control weeds in rice is a herbicide with the active ingredient metamifop. This study aimed to determine the effectiveness of the herbicide with the active ingredient metamifop 150 g/l in controlling weeds and its effect on lowland rice's growth and yield components. This experiment was carried out at the SPLPP Faculty of Agriculture, Padjadjaran University, Ciparay, Baleendah District, Bandung Regency, West Java, from June to September 2022. The research used an experimental method with Randomized Block Design with 6 treatments and 4 replications. The treatment consisted of the herbicide metamifop dose of 150 g/l with a level of 1.125; 1.50; 1,875; 2.25 l/ha, manual weeding, and control. The results showed that the herbicide metamifop 150 g/l at a dose of 1.125-2.25 l/ha was effective in controlling total weed up to 6 weeks after application without causing phytotoxicity to paddy. The herbicide metamifop 150 g/l affected the growth and yield of paddy.