The global fruit intake is significantly influenced by tropical fruits. However, the majority of earlier research only found volatile and bulk components, their metabolomes have not yet been thoroughly studied. This study's objective was to use GC-HRMS to significant biopotential chemicals in Artocarpus heterophyllus Lam. flakes and seeds from both wild and domesticated varieties. Sixty-two phytochemical components were found in the methanolic extract of A. heterophyllus based on the mass fragment, retention duration and molecular weight by GC-HRMS analysis, in which fifteen are the major compounds as found out in the study. This is the first report on the flakes and seeds of genotypes of cultivated and wild jackfruit.