Plants are known as good sources of natural therapeutic agents. Plants generally contain secondary metabolites like phenolics, flavonoids, glycosides, coumarins, saponins, terpenoids and alkaloids etc. which reveal their specific characteristic properties and attribute to their pharmacological properties. Karonda are popularly consumed fruits in world because of its simple taste, high nutritional value and potential health benefits. In the present investigation, different parts of Carrisa carandas L. (fruits, seeds, stem, and leaves) were subjected to estimate total phenolic and flavonoid contents as well as extracts of these plant parts were also evaluated for their antioxidant activity by DPPH assay. Results of the present study indicated the presence of good quantity of total phenols and flavonoid contents in all the selected plant parts. The maximum phenolic content in while leaves of the plant were found to possess the highest phenolic content (28.96±4.26 mg QE/gdw) than other parts. Flowers were found to have the maximum flavonoid content (78.93±10.35mg GAE/gdw). The maximum free radical scavenging activity in was shown by leaves with the lowest IC50 value (10.675 mg/L). All experiments were done in triplicates. One way ANOVA analysis showed lack of significant differences in antioxidant activity and total phenolic and flavonoid contents among all the selected plant parts.