The present study investigates the antimicrobial potential of Naringi crenulata (Roxb.) Nicolson stem and leaf extracts against bacterial and fungal pathogens. Solvent extracts (hexane, ethyl acetate, and methanol) were prepared using the Soxhlet extraction method and screened for antibacterial activity against Staphylococcus aureus, Bacillus cereus, Staphylococcus epidermidis, Escherichia coli, Enterobacter aerogenes, and Pseudomonas aeruginosa, as well as antifungal activity against Candida albicans and Aspergillus niger using the agar well diffusion method.

Leaf extracts demonstrated greater antimicrobial efficacy compared to stems, with ethanol and hexane extracts exhibiting the highest activity. S. aureus was highly susceptible to ethanol leaf extract (4.4 cm zone of inhibition), whereas B. cereus showed significant inhibition with hexane (2.7 cm) and ethanol extracts (0.64 cm). P. aeruginosa exhibited slight inhibition with ethanol extract (1.015 cm), while E. coli and E. aerogenes were resistant to all treatments. Strong antifungal activity was observed, particularly against C. albicans and A. niger, with ethyl acetate and methanol leaf extracts producing the highest inhibition.