ARCHIVES
VOL. 10, ISSUE 7 (2025)
Synthesis, characterization of zinc oxide nanoparticles using fruit peel of muskmelon and evaluation of their biological potential
Authors
Bhupendra Tanwar, Pawan Kumar Kansotiya, Anupama Goyal
Abstract
In this study, zinc oxide nanoparticles (ZnONPs) were successfully synthesized using the extract of musk melon (Cucumis melo) peel through a green synthesis approach. Characterization of the synthesized ZnONPs revealed a distinct UV-Vis absorption peak at 375 nm, indicative of quantum confinement effects in nanostructures, corroborated by previous studies on plant-mediated ZnO synthesis. Fourier-transform infrared spectroscopy (FTIR) analysis confirmed the presence of functional groups, including hydroxyl (-OH) and carbonyl (C=O), essential for the reduction and stabilization of ZnONPs, reflecting the role of bioactive compounds in the musk melon peel extract. Field emission scanning electron microscopy (FESEM) demonstrated the spherical morphology of the nanoparticles, with sizes ranging from 20-40 nm, while energy dispersive X-ray spectroscopy (EDX) confirmed the elemental composition of Zn (63.22%) and O (36.78%). X-ray diffraction (XRD) analysis revealed the crystalline nature of the ZnONPs, aligning with the hexagonal wurtzite structure of ZnO. The zeta potential of -22.5 mV indicated moderate stability in aqueous solutions. Biologically, ZnONPs exhibited significant antioxidant (IC50 = 2187.06 µg/ml), antidiabetic (IC50 = 1721.30 µg/ml), and anti-inflammatory (IC50 = 11018.17 µg/ml), surpassing those of the crude extract. The enhanced biological activities can be attributed to the increased surface area and reactivity of the nanoparticles, alongside the stabilization conferred by the bioactive compounds in the peel extract. These findings underscore the potential of musk melon peel extract in green nanotechnology for synthesizing ZnONPs with significant biomedical applications, suggesting pathways for future in vivo studies and scalability for industrial applications.
Download
Pages:8-12
How to cite this article:
Bhupendra Tanwar, Pawan Kumar Kansotiya, Anupama Goyal "Synthesis, characterization of zinc oxide nanoparticles using fruit peel of muskmelon and evaluation of their biological potential". International Journal of Botany Studies, Vol 10, Issue 7, 2025, Pages 8-12
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.