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VOL. 11, ISSUE 1 (2026)
Impact of environmental conditions on antifungal properties of medicinal plants
Authors
Dr. Digambar Subhashrao Pawar
Abstract
Fungal infections cause major illness and mortality in humans, animals,
and plants, making them a serious to global health. The investigation of alternative
treatments has been spurred by the emergence of drug-resistant fungal strains
and the drawbacks of existing antifungal medications, including toxicity and
the possibility of resistance. Because of their bioactive phytochemicals,
medicinal plants have become a promising source of antifungal drugs. These
substances, which include phenols, alkaloids, terpenoids, and phytosterols,
have a variety of modes of action, including inducing mitochondrial
malfunction, disrupting fungal cell membranes, and inhibiting the formation of
cell walls. so we must focus on other alternatives that are biologically safe and
nonhazardous. In the present investigation, aqueous
extract of leaf of Calotropis gigantea and Dolichandrone falcata which
were found antifungal against Phytophthora infestans were
exposed to various physical factors such as Autoclave, Temperature, pH,
Humidity etc. Specific fungus was used to test the exposed extracts. The influence of physical factors were investigated by subjecting the
extract to altering conditions of the parameters chosen for a specified time
period and then observing the effect as a function of change in the extract's
MIC against the test organism. Three replicates were kept in addition to the
control, and the experiments were performed three times. The Finding suggested that efficacy of leaf extracts against tested
fungus were affected by physical factors. Results revealed that autoclaving,
high temperature, alkaline pH and high humidity decrease the antifungal
activity of plant extracts.
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Pages:352-354
How to cite this article:
Dr. Digambar Subhashrao Pawar "Impact of environmental conditions on antifungal properties of medicinal plants". International Journal of Botany Studies, Vol 11, Issue 1, 2026, Pages 352-354
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