ARCHIVES
VOL. 11, ISSUE 3 (2026)
Investigation of phytochemicals, antibacterial and antioxidant assays of Cryptocarya amygdalina Nees leaf extract
Authors
Padmini Parida, Sandeep Kumar Mohanta, Aryaputri Bedaprabha, Goutam Charan Das, Abanikanta Bhadra, Durga Prasad Barik
Abstract
Cryptocarya amygdalina
Nees, a medicinal tree of the Lauraceae family, is widely distributed across
Peninsular Myanmar, Southern China, Bhutan, Thailand, Nepal, and several Indian
states including Odisha, West Bengal, Arunachal Pradesh, Assam, Meghalaya,
Sikkim, and Tripura. This plant is reported to possess several pharmacological
properties like anti-inflammatory, cholinesterase inhibitory, anti-fungal,
anti-oxidant, anti-plasmodial, anti-tuberculosis, insecticidal, and
anti-cytotoxic. Hence, this study is undertaken to determine the phytochemical
composition present in leaf extracts using various solvents (aqueous, methanol,
acetone, chloroform, and n-hexane) and to evaluate the antibacterial activity
and antioxidant properties of the methanolic leaf extract. Preliminary
phytochemical analysis revealed the presence of several groups of bioactive
compounds, such as alkaloids, saponins, phytosterols, phenolic compounds,
glycosides, tannins, flavonoids, coumarins, steroids, quinones and terpenoids.
The aqueous leaf extract showed the highest diversity of compounds.
Antibacterial activity of the methanolic leaf extract was tested against four
human pathogenic bacteria such as Vibrio cholerae and Salmonella
typhi (Gram-negative), and Streptococcus mutans and Streptococcus
pyogenes (Gram-positive). The methanolic leaf extracts demonstrated
significant antibacterial activity compared to the standard antibiotic
ciprofloxacin. Additionally, the methanolic leaf extract exhibited antioxidant
potential in DPPH radical scavenging assays with an IC50 value of
64.97±0.37 μg/ml. These findings highlight the therapeutic potential of C.
amygdalina leaves as a source of natural antibacterial and antioxidant
agents, providing a foundation for further drug discovery and pharmacological
exploration.
Download
Pages:1-5
How to cite this article:
Padmini Parida, Sandeep Kumar Mohanta, Aryaputri Bedaprabha, Goutam Charan Das, Abanikanta Bhadra, Durga Prasad Barik "Investigation of phytochemicals, antibacterial and antioxidant assays of <i>Cryptocarya amygdalina </i>Nees leaf extract". International Journal of Botany Studies, Vol 11, Issue 3, 2026, Pages 1-5
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.